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Clinical Pediatrics, Vol. 26, No. 9, 441-446 (1987)
DOI: 10.1177/000992288702600902

Asymptomatic Toxocariasis in Children

A Prospective Study and Treatment Trial

Joel L. Bass

Departments of Pediatrics and Ophthalmology, Framingham Union Hospital, Framingham, Massachusetts, Boston University, Boston, Massachusetts

Kishor A. Mehta

Departments of Pediatrics and Ophthalmology, Framingham Union Hospital, Framingham, Massachusetts, Boston University, Boston, Massachusetts

Lawrence T. Glickman

School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania

Richard Blocker

Departments of Pediatrics and Ophthalmology, Framingham Union Hospital, Framingham, Massachusetts, Boston University, Boston, Massachusetts

Bonnie M. Eppes

Departments of Pediatrics and Ophthalmology, Framingham Union Hospital, Framingham, Massachusetts

Screening of 153 Hispanic children attending a Hospital-based primary care clinic revealed a 16 percent prevalence of Toxocara canis infection. Infections were found in other household occupants for half of these children. Follow-up of 20 children (for periods of up to 7 years) with asymptomatic T. canis infection failed to demonstrate any clinical sequelae. However, longer periods would be necessary to entirely discount the possibility of latent ocular disease. Treatment with thiabendazole did not appear to alter the course of the infection in a controlled 1-year evaluation as measured by eosinophil counts and specific T. canis antibody titers.


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