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Clinical Pediatrics, Vol. 26, No. 7, 366-368 (1987)
DOI: 10.1177/000992288702600709

Reviews

Congenital Absence of Lacrimal Puncta and of All Major Salivary Glands: Case Report and Literature Review

Hirohiko Higashino

Department of Pediatrics, Kansai Medical University, Fumizonocho 1, Moriguchi, Osaka 570, Japan

Tsuguo Horii

Department of Pediatrics, Kansai Medical University, Fumizonocho 1, Moriguchi, Osaka 570, Japan

Yoshiaki Ohkusa

Department of Ophthalmology, Kansai Medical University, Fumizonocho 1, Moriguchi, Osaka 570, Japan

Hiroshi Ohkuma

Department of Ophthalmology, Kansai Medical University, Fumizonocho 1, Moriguchi, Osaka 570, Japan

Chiyonori Ino

Department of Otolaryngology, Kansai Medical University, Fumizonocho 1, Moriguchi, Osaka 570, Japan

Midori Nakazawa

Department of Radiology, Kansai Medical University, Fumizonocho 1, Moriguchi, Osaka 570, Japan

Haruaki Izumi

Clinical Pathology, Kansai Medical University, Fumizonocho 1, Moriguchi, Osaka 570, Japan

Yohnosuke Kobayashi

Department of Pediatrics, Kansai Medical University, Fumizonocho 1, Moriguchi, Osaka 570, Japan

A 7-year-old girl had dry mouth and recurrent infections of the lacrimal fistulae with decreased lacrimal secretion. All four puncta were absent, and a Schirmer test showed decreased lacrimal secretion. Salivary gland imaging with sodium pertechnetate 99mTcO4 showed absence of all major salivary glands. Lower lip biopsy disclosed normal structure of the salivary gland. No evidence of abnormal inheritance patterns could be demonstrated.


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