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Proposed Guidelines for Screening of Metabolic and Endocrine Diseases of Dependent Neonates of the U.S. Armed Forces

Derived from a Survey of State Guidelines for Neonatal Screening of Metabolic Diseases

Department of Pediatrics, Walter Reed Army Medical Center and the Uniformed Services University of the Health Sciences, Bethesda, Maryland

State regulations for neonatal screening for metabolic diseases do not optimally serve the needs of the dependents of the U.S. Armed Forces. Guidelines are therefore proposed for the neonatal screening for metabolic disease based both on responses received across the United States and on the unique needs of the U.S. Armed Forces. The guidelines agree with the policies outlined by various national medical and scientific organizations. It is suggested that neonates be screened for phenylketonuria (PKU), hypothyroidism, galactosemia, and maple syrup urine disease (MSUD). The screening program is cost-effective and feasible. Prior to implementing the program throughout the U.S. military, a pilot program based at the Armed Forces Institute of Pathology should be started.

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