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Clinical Pediatrics, Vol. 25, No. 8, 409-411 (1986)
DOI: 10.1177/000992288602500806

Differential Leukocyte Count in Infants of Diabetic Mothers

Increased Band Count Associated with Macrosomia

Francis Mimouni

Department of Neonatology, the University of Tel Aviv, Sackler Medical School

Shimon Porat

Department of Neonatology, the University of Tel Aviv, Sackler Medical School

Paul Merlob

Department of Neonatology, the University of Tel Aviv, Sackler Medical School

Rina Zaizov

Department of Pediatric Hematology, Beilinson Medical Center, Petah Tiqva and the University of Tel Aviv, Sackler Medical School, Israel

Salomon H. Reisner

Department of Neonatology, the University of Tel Aviv, Sackler Medical School

The differential leukocyte count was studied within the first 24 hours of life in 115 infants of diabetic mothers (IDMs) appropriate for gestational age (AGA), 16 IDMs large for gestational age (LGA), 104 infants of non-diabetic mothers (INM's) AGA, and 22 INMs-LGA. A significant "shift to the left" was found in IDM's-LGA only. The usual causes of "shift to the left" such as maternal hypertension or fever, respiratory distress syndrome, meconium aspiration, neonatal asphyxia, sepsis, convulsions, or hypoglycemia could not explain this finding. It is hypothesized that increased glucocorticoid secretion may possibly play a role.


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