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Improved Survival and Short-term Outcome of Inborn "Micropremies"

Section on Newborn Pediatrics, Pennsylvania Hospital, Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania

Soraya Abbasi

Section on Newborn Pediatrics, Pennsylvania Hospital, Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania

Vinod K. Bhutani

Section on Newborn Pediatrics, Pennsylvania Hospital, Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania

Frank W. Bowen, JR

Section on Newborn Pediatrics, Pennsylvania Hospital, Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania

Survival and significant chronic morbidity were determined by retrospective chart review for 107 inborn "micropremies." "Micropremies" are defined as appropriate-for-gestational age neonates of <1,001 grams and 28 weeks gestation. The overall survival rate for "micropremies" was 64 percent, ranging from 20 percent at 24 weeks to 83 percent at 27 weeks gestation. Race and sex are important determinants of survival in these infants. The incidence of severe, chronic morbidity in "micropremies" is relatively low. The acceptable outcome for "micropremies" supports aggressive perinatal management for fetuses as low as 24 to 25 weeks gestation. However, it is important for physicians to use current statistics from their own institutions when counseling parents and making management decisions.

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