Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

Click here for FREE ACCESS to this landmark database

SAGETRACK

Sign In to gain access to subscriptions and/or personal tools.
Clinical Pediatrics
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Whyte, M. P.
Right arrow Articles by Schnaper, H. W.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Whyte, M. P.
Right arrow Articles by Schnaper, H. W.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Cystinosis Presenting with Features Suggesting Bartter Syndrome

Case Report and Literature Review

Michael P. Whyte

Metabolic Research Unit, Shriners Hospital for Crippled Children, 2001 South Lindbergh Blvd., St. Louis, MO 63131

Sudah Shaheb

From the Metabolic Research Unit, Shriners Hospitals for Crippled Children; the Division of Bone and Mineral Metabolism, Department of Medicine, The Jewish Hospital of St. Louis; Washington University School of Medicine; and Edward Mauinckrodt Department of Pediatrics, St. Louis ChHdren's Hospital, St. Louis, Missouri.

H. William Schnaper

From the Metabolic Research Unit, Shriners Hospitals for Crippled Children; the Division of Bone and Mineral Metabolism, Department of Medicine, The Jewish Hospital of St. Louis; Washington University School of Medicine; and Edward Mauinckrodt Department of Pediatrics, St. Louis ChHdren's Hospital, St. Louis, Missouri.

Features suggestive of Bartter syndrome (hypokalemia, hypochloremic metabolic alkalosis, and normal blood pressure despite hyperreninemia and hyperaldoster onism) were found in a 5-year-old black child with cystinosis and Fanconi syndrome. Review of his medical records revealed that these abnormalities had probably been present when he first became clinically ill at 2 years of age. Sodium and potassium chloride supplementation lead to improved growth and strength, partial correction of his electrolyte abnormalities, and a decrease in markedly elevated plasma renin activity. Literature review disclosed a similar presentation in four Caucasian children with cystinosis.

Biochemical findings compatible with Bartter syndrome can occur together with evidence of generalized proximal renal tubular dysfunction (Fanconi syn drome) in nephropathic cystinosis.

Clinical Pediatrics, Vol. 24, No. 8, 447-451 (1985)
DOI: 10.1177/000992288502400806
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?