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Clinical Pediatrics
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Eczema Herpeticum of the Child

An Unusual Manifestation of Herpes Simplex Virus Infection

D. Ingrand

Laboratoire de Bacteriologie-Virologie, Groupe hospitalier Pitie-Salpetriere, Paris, Centre hospitalier de Pontoise, and Centre hospitalier Intercommunal de Crèteil, France

I. Briquet

Laboratoire de Bacteriologie-Virologie, Groupe hospitalier Pitie-Salpetriere, Paris, Centre hospitalier de Pontoise, and Centre hospitalier Intercommunal de Crèteil, France

J.M. Babinet

Laboratoire de Bacteriologie-Virologie, Groupe hospitalier Pitie-Salpetriere, Paris, Centre hospitalier de Pontoise, and Centre hospitalier Intercommunal de Crèteil, France

Ph. Reinert

Laboratoire de Bacteriologie-Virologie, Groupe hospitalier Pitie-Salpetriere, Paris, Centre hospitalier de Pontoise, and Centre hospitalier Intercommunal de Crèteil, France

J.M. Huraux

Laboratoire de Bacteriologie-Virologie, Groupe hospitalier Pitie-Salpetriere, Paris, Centre hospitalier de Pontoise, and Centre hospitalier Intercommunal de Crèteil, France

Two children aged 7 months with eczema herpeticum received treatment consisting of intravenous acyclovir and human plasma with a high titer of herpes simplex virus antibodies. One recovered following two recurrences, but the other died rapidly, suffering both septicemia due to Pseudomonas aeruginosa and herpetic encephalitis. In both cases, the virus involved was a herpes simplex virus type 1 (HSV 1). The various isolates obtained before, during and after treatment remained equally sen sitive to acyclovir. These observations highlight three points: (1) the unpredictable and sometimes dramatic development of eczema herpeticum in the young child; (2) the urgency of early diagnosis and treatment; (3) the role of environment in viral contamination.

Clinical Pediatrics, Vol. 24, No. 11, 660-663 (1985)
DOI: 10.1177/000992288502401118
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