This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Granati, B. Articles by Sartori, E. Search for Related Content PubMed PubMed Citation Articles by Granati, B. Articles by Sartori, E. Social Bookmarking                         What's this?

Efficacy and Safety of the "Integral" Phototherapy for Neonatal Hyperbilirubinemia

Results of a Follow-up at 6 Years of Age

Dept. of Pediatrics, University of Padova, Via Giustiniani 3, 35128 Padova, Italy

G. Largajolli

Dept. of Pediatrics, University of Padova, Via Giustiniani 3, 35128 Padova, Italy

F.F. Rubaltelli

Dept. of Pediatrics, University of Padova, Via Giustiniani 3, 35128 Padova, Italy

P. Pollazzon

Dept. of Pediatrics, University of Padova, Via Giustiniani 3, 35128 Padova, Italy

M. Bottos

Dept. of Pediatrics, University of Padova, Via Giustiniani 3, 35128 Padova, Italy

E. Sartori

Dept. of Pediatrics, University of Padova, Via Giustiniani 3, 35128 Padova, Italy

One hundred and ten full-term newborns were treated with integral phototherapy (IP) in the first week of life for hyperbilirubinemia (peak bilirubin concentration, 19.5 ± 2.8 mg/dl). IP was provided by an apparatus which irradiated the infants over the entire skin surface with four visible blue light lamps placed around the body at a mean distance of only 20 cm. The irradiance of the lamps at the skin surface was 0.350 mW/sq cm, in the wavelength range between 425 and 475 nm. The IP resulted in a 48-hour bilirubin decline rate of 0.163 mg/dl/h. After a mean exposure of 78 ± 32 h, the mean plasma bilirubin level was 8.4 ± 0.8 mg/dl. One hundred and ten comparable nonjaundiced infants were studied as controls.

At 6 years of age, both groups of subjects were called for a follow-up concerning growth, visual, and hearing functions, and neuro-developmental status. The follow-up was completed in 81 children of the IP group (73.6%) and in 89 of the controls (80.6%). There were no significant differences in the studied parameters between the two groups. The study concludes that IP appears to be an effective and safe treatment for jaundiced infants. IP employs less radiant energy from the lamp source than the traditional apparatus, but delivers this energy to a larger skin surface area.

Clinical Pediatrics, Vol. 23, No. 9, 483-486 (1984)
DOI: 10.1177/000992288402300905


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?

This article has been cited by other articles:

				E. Matichard, A. Le Henanff, A. Sanders, J. Leguyadec, B. Crickx, and V. Descamps Effect of Neonatal Phototherapy on Melanocytic Nevus Count in Children Arch Dermatol, December 1, 2006; 142(12): 1599 - 1604. [Abstract] [Full Text] [PDF]

				V. Wong, W.-X. Chen, and K.-Y. Wong Short- and Long-Term Outcome of Severe Neonatal Nonhemolytic Hyperbilirubinemia J Child Neurol, April 1, 2006; 21(4): 309 - 315. [Abstract] [PDF]

				W.-X. Chen and V. Wong Visual Evoked Potentials in Neonatal Hyperbilirubinemia J Child Neurol, January 1, 2006; 21(1): 58 - 62. [Abstract] [PDF]

				P. George and M. Lynch Ohmeda Biliblanket vs Wallaby Phototherapy System for the Reduction of Bilirubin Levels in the Home-Care Setting Clinical Pediatrics, March 1, 1994; 33(3): 178 - 180. [PDF]

				D. Woodall and J. G. Karas A New Light on Jaundice: A Pilot Study Clinical Pediatrics, June 1, 1992; 31(6): 353 - 356. [PDF]