Clinical Pediatrics

 

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Clinical Pediatrics, Vol. 23, No. 6, 352-353 (1984)
DOI: 10.1177/000992288402300611

Valproic Acid and Congenital Malformations

A Case Report

Maj Eric W. Bantz

USA, Department of Pediatrics, 97th General Hospital, Frankfurt, West Germany, APO New York 09757

An infant exposed in utero to valproic acid was born with multiple congenital malformations, including duodenal atresia, lumbar vertebral fusion, thoracolumbar scoliosis, renal abnormalities, diastasis recti abdominis, depigmentation of the eye brows, and a large hemangioma. The child had neonatal hyperbilirubinemia and postnatal growth deficiency. This case report is an addition to the literature im plicating valproic acid as a human teratogen.


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