Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

Click here for more information

SAGETRACK

Sign In to gain access to subscriptions and/or personal tools.
Clinical Pediatrics
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Brook, I.
Right arrow Articles by Gober, A. E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Brook, I.
Right arrow Articles by Gober, A. E.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Emergence of Beta -lactamase-prod uci n g Aerobic and Anaerobic Bacteria in the Oropharynx of Children Following Penicillin Chemotherapy

Itzhak Brook

Naval Medical Research Institute, National Naval Medical Center, Bethesda, MD 20814

Alan E. Gober

The acquisition of beta-lactamase-producing aerobic and anaerobic bacteria was investigated in 21 children treated with penicillin for otitis media or pharyngitis and in 18 untreated control children. Beta-lactamase-producers were isolated in three children before and in ten children after treatment (p = 0.04). Although the variety of bacterial species isolated did not change following treatment, beta-lactamase-producing Bacteroides melaninogenicus, B. orulis, and Branhamella ca tarrhalis were encountered only after therapy, while some beta-lactamase-producing Staphylococcus aureus and Hemophilus influenzae were found before treatment. The incidence of beta-lactamase- producers did not increase in the control children. Spread of beta-lactamase-producers to household contacts by 12 treated and 13 normal control children also was studied. Ten of the treated children and 15 of 33 of the household contacts harbored beta-lactamase-producers, while none were found in normal control children and only two were found in 27 of their household contacts (comparison of the two household contacts, p < 0.01).

Clinical Pediatrics, Vol. 23, No. 6, 338-341 (1984)
DOI: 10.1177/000992288402300608
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
 CLIN PEDIATRHome page
I. Brook
Penicillin Failure in the Treatment of Acute and Relapsing Tonsillopharyngitis Is Associated With Copathogens and Alteration of Microbial Balance: A Role for Cephalosporins
Clinical Pediatrics, May 1, 2007; 46(4_suppl): 17S - 24S.
[Abstract] [PDF]

Home page
 Arch Otolaryngol Head Neck SurgHome page
I. Brook
Bacteriology of chronic sinusitis and acute exacerbation of chronic sinusitis.
Arch Otolaryngol Head Neck Surg, October 1, 2006; 132(10): 1099 - 1101.
[Abstract] [Full Text] [PDF]

Home page
 J Antimicrob ChemotherHome page
S. Nyfors, E. Kononen, R. Syrjanen, E. Komulainen, and H. Jousimies-Somer
Emergence of penicillin resistance among Fusobacterium nucleatum populations of commensal oral flora during early childhood
J. Antimicrob. Chemother., January 1, 2003; 51(1): 107 - 112.
[Abstract] [Full Text] [PDF]

Home page
 Arch Otolaryngol Head Neck SurgHome page
I. Brook, P. Yocum, E. H. Frazier, and J. G. Bartlett
Bacteriology and {beta}-Lactamase Activity in Acute and Chronic Maxillary Sinusitis
Arch Otolaryngol Head Neck Surg, April 1, 1996; 122(4): 418 - 423.
[Abstract] [PDF]

Home page
 Arch Otolaryngol Head Neck SurgHome page
I. Brook and A. E. Gober
Role of Bacterial Interference and {beta}-Lactamase--Producing Bacteria in the Failure of Penicillin to Eradicate Group A Streptococcal Pharyngotonsillitis
Arch Otolaryngol Head Neck Surg, December 1, 1995; 121(12): 1405 - 1409.
[Abstract] [PDF]

Home page
 Arch Otolaryngol Head Neck SurgHome page
I. Brook, D. H. Thompson, and E. H. Frazier
Microbiology and Management of Chronic Maxillary Sinusitis
Arch Otolaryngol Head Neck Surg, December 1, 1994; 120(12): 1317 - 1320.
[Abstract] [PDF]

Home page
 Arch Fam MedHome page
W. Huck, B. D. Reed, R. W. Nielsen, R. T. Ferguson, D. W. Gray, G. K. Lund, D. H. ZoBell, and M. B. Moster
Cefaclor vs Amoxicillin in the Treatment of Acute, Recurrent, and Chronic Sinusitis
Arch Fam Med, May 1, 1993; 2(5): 497 - 503.
[Abstract] [PDF]

Home page
 Arch Otolaryngol Head Neck SurgHome page
C. I. Timon, M. T. Cafferkey, and M. Walsh
Fine-Needle Aspiration in Recurrent Tonsillitis
Arch Otolaryngol Head Neck Surg, June 1, 1991; 117(6): 653 - 656.
[Abstract] [PDF]

Home page
 Arch Otolaryngol Head Neck SurgHome page
P. A. Foote Jr and I. Brook
Penicillin and Clindamycin Therapy in Recurrent Tonsillitis: Effect of Microbial Flora
Arch Otolaryngol Head Neck Surg, July 1, 1989; 115(7): 856 - 859.
[Abstract] [PDF]

Home page
 Arch Otolaryngol Head Neck SurgHome page
D. Ophir, J. Bawnik, Y. Poria, M. Porat, and G. Marshak
Peritonsillar Abscess: A Prospective Evaluation of Outpatient Management by Needle Aspiration
Arch Otolaryngol Head Neck Surg, June 1, 1988; 114(6): 661 - 663.
[Abstract] [PDF]

Home page
 Arch Otolaryngol Head Neck SurgHome page
I. Brook
Emergence and Persistence of {beta}-Lactamase--Producing Bacteria in the Oropharynx Following Penicillin Treatment
Arch Otolaryngol Head Neck Surg, June 1, 1988; 114(6): 667 - 670.
[Abstract] [PDF]

Home page
 Arch Pediatr Adolesc MedHome page
I. Brook
Microbiology of Retropharyngeal Abscesses in Children
Arch Pediatr Adolesc Med, February 1, 1987; 141(2): 202 - 204.
[Abstract] [PDF]