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Clinical Pediatrics
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Fetal-neonatal Uremia in Advanced Maternal Diabetes

Fernando R. Moya

Department of Pediatrics and the Division of Maternal-Fetal Medicine of the Department of Obstetrics and Gynecology, Yale University School of Medicine, New Haven, Connecticut

E. Albert Reece

Department of Pediatrics and the Division of Maternal-Fetal Medicine of the Department of Obstetrics and Gynecology, Yale University School of Medicine, New Haven, Connecticut

John C. Hobbins

Department of Pediatrics and the Division of Maternal-Fetal Medicine of the Department of Obstetrics and Gynecology, Yale University School of Medicine, New Haven, Connecticut

A symmetrically growth retarded premature infant was born to a mother with advanced diabetic nephropathy, chronic renal failure, and hypertension, and man aged with aggressive medical therapy without the use of dialysis. The neonatal course was uncomplicated, except for cord blood creatinine and BUN concentrations of 4.7 mg/dl and 116 mg/dl, respectively, that fell to 1.1 mg/dl and 44 mg/dl by 2 days of age. Strict glucose control, careful management of the metabolic abnor malities of uremia, and periodic surveillance of fetal well-being led to a successful pregnancy.

Clinical Pediatrics, Vol. 23, No. 4, 229-231 (1984)
DOI: 10.1177/000992288402300409
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