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Clinical Pediatrics
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Direct Hyperbilirubinemia Complicating ABO Hemolytic Disease of the Newborn

Yakov Sivan

Paul Merlob

Jacob Nutman

Salomon H. Reisner

A retrospective study of the diagnostic implications of conjugated hyperbilirubinemia com plicating ABO hemolytic disease of the newborn (HDN) was done by studying the records of 264 infants with ABO-HDN. Direct hyperbilirubinemia was found to complicate ABO-HDN in 3 per cent of the infants, all being full term. Eighty-seven per cent were female and familial occurrence was noted in half of the cases. Most of the infants presented with anemia on the first day of life. Our data suggest that this is a benign complication of ABO-HDN which clears within a month.

Clinical Pediatrics, Vol. 22, No. 8, 537-538 (1983)
DOI: 10.1177/000992288302200802


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P. Merlob, A. Litwin, L. Lazar, and R. Zaizov
Neonatal ABO Incompatibility: Complicated by Hemoglobinuria and Acute Renal Failure
Clinical Pediatrics, April 1, 1990; 29(4): 219 - 222.
[Abstract] [PDF]