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Clinical Pediatrics, Vol. 22, No. 3, 190-192 (1983)
DOI: 10.1177/000992288302200306

Lidocaine Toxicity from Topical Mucosal Application

With a Review of the Clinical Pharmacology of Lidocaine

Howard C. Mofenson

Poison Control Center and Department of Pediatrics, Nassau County Medical Center, East Meadow, New York

Thomas R. Caraccio

Poison Control Center and Department of Pediatrics, Nassau County Medical Center, East Meadow, New York

Harvey Miller

Poison Control Center and Department of Pediatrics, Nassau County Medical Center, East Meadow, New York

Joseph Greensher

Poison Control Center and Department of Pediatrics, Nassau County Medical Center, East Meadow, New York

A case is reported of an infant who experienced seizures while being treated with a topical lidocaine 2% solution (Xylocaine® 2% Viscous) for teething. The pharmacology of lidocaine is reviewed to alert physicians to the potential dangers of topical mucosal application of these preparations.


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