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Clinical Pediatrics
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Isolated Testicular Relapse Five Years After Cessation of Chemotherapy for Acute Lymphoblastic Leukemia

Jen-Yih Chu, M.D., Ph.D.

Department of Pediatrics, Cardinal Glennon Memorial Hospital for Children, St. Louis, Missouri

Dennis M. O'Connor, M.D.

Department of Pediatrics, Cardinal Glennon Memorial Hospital for Children, St. Louis, Missouri

Thomas V. Cradock, M.D.

Department of Pediatrics, Cardinal Glennon Memorial Hospital for Children, St. Louis, Missouri

Gordon B. Gale, M.D.

Department of Pediatrics, Cardinal Glennon Memorial Hospital for Children, St. Louis, Missouri

A 12-year-old boy was diagnosed as having acute lymphoblastic leukemia (ALL) at the age of 2 years 10 months. Chemotherapy was discontinued after 33 months of continuous remisson of ALL. Isolated testicular relapse occurred 5 years after . cessation of treatment. Isolated testicular infiltration if it occurs, usually does so within one year after discontinuing treatment. Late bone marrow or extramedul lary relapse usually does not occur after four years post therapy. Testicular relapse in this patient occurred five years after completing chemotherapy.

Clinical Pediatrics, Vol. 21, No. 6, 376-377 (1982)
DOI: 10.1177/000992288202100612
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