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Clinical Pediatrics
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Hypoelectrolytemia as a Presentation and Complication of Cystic Fibrosis

Richard Ruddy, M.D.

Department of Pediatrics, University of Pennsylvania School of Medicine, and the Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

Robert Anolik, M.D.

Department of Pediatrics, University of Pennsylvania School of Medicine, and the Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

Thomas F. Scanlin, M.D.

Department of Pediatrics, University of Pennsylvania School of Medicine, and the Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

We describe three patients with cystic fibrosis (CF) with four episodes of hy poelectrolytemia, two of which were associated with documented metabolic al kalosis. CF should be included in the differential diagnosis of infants and children presenting with hypoelectrolytemia and metabolic alkalosis. Patients with CF are at risk of developing severe hypochloremia in hot weather and during intercurrent illness. An abrupt diminution of oral intake is an important suggestive sign, alerting the physician to look for the development of hypoelectrolytemia.

Clinical Pediatrics, Vol. 21, No. 6, 367-369 (1982)
DOI: 10.1177/000992288202100609
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