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Clinical Pediatrics
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Adrenal Cortical Carcinoma in a 4-Year-Old Child

Temporal Changes in Steroid Secretion

Roberto Lanes

Department of Endocrinology, Hospital Central de las Fuerzas Armadas "Dr. Carlos Arvelo," Caracas, Venezuela

Saul Gonzalez

Department of Endocrinology, Hospital Central de las Fuerzas Armadas "Dr. Carlos Arvelo," Caracas, Venezuela

Oswaldo Obregon

Department of Endocrinology, Hospital Central de las Fuerzas Armadas "Dr. Carlos Arvelo," Caracas, Venezuela

A case is reported of a 4-year-old female with an adrenal cortical carcinoma that developed at the site of a previously removed adrenal gland. Initially, the tumor was only virilizing, but with time, it also became the source of a large secretion of glucocorticoids and, to a lesser degree, mineralocorticoids. It is one of the largest and most functional tumors described in a child.

Clinical Pediatrics, Vol. 21, No. 3, 164-166 (1982)
DOI: 10.1177/000992288202100305
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