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Clinical Pediatrics
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Cryptococcal Osteomyelitis

Report of a Case and a Review of the Literature

Margaret R. Hammerschlag

departments of Pediatrics, Pathology, and Radiology, Kings County Hospital, Downstate Medical Center, Brooklyn, New York

Javier Domingo

departments of Pediatrics, Pathology, and Radiology, Kings County Hospital, Downstate Medical Center, Brooklyn, New York

Jack O. Haller

departments of Pediatrics, Pathology, and Radiology, Kings County Hospital, Downstate Medical Center, Brooklyn, New York

David Papayanopulos

departments of Pediatrics, Pathology, and Radiology, Kings County Hospital, Downstate Medical Center, Brooklyn, New York

A case is reported of isolated cryptococcal osteomyelitis in an 11-year-old girl without any detectable underlying disease. The patient was successfully treated for six weeks with intravenous amphotericin B and oral 5-flucytosine. There is only one other case of cryptococcal osteomyelitis reported in the English medical literature in a child. Over 50 per cent of individuals with this infection will have an underlying condition which may have predisposed them to acquiring this disease.

Clinical Pediatrics, Vol. 21, No. 2, 109-112 (1982)
DOI: 10.1177/000992288202100208
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