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Clinical Pediatrics
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Ocular Manifestations of the Fetal Hydantoin Syndrome

G. Robert Hampton

Retina Division, Department of Ophthalmology, Albany Medical College, Albany, New York

Jaime I. Krepostman

Retina Division, Department of Ophthalmology, Albany Medical College, Albany, New York

Eleven per cent of infants exposed to hydantoins in utero have a recogniz able pattern of abnormalities with serious clinical consequences. This report of a child born to a mother taking diphenylhydantoin emphasizes the ocular find ings.

At birth and subsequent 8-month exam, a girl was noted to have microph thalmus, prominent iris vessels, and an inferior iris and choroidal colobma. Relation of these anomalies to teratogenic properties of diphenylhydantoin is discussed.

Clinical Pediatrics, Vol. 20, No. 7, 475-478 (1981)
DOI: 10.1177/000992288102000710
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?