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Clinical Pediatrics
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Respiratory Syncytial Virus Infection

Ten-Year Follow-up

John T. Twiggs

Department of Pediatrics, Mayo Clinic and Mayo Foundation, Rochester, Minnesota

Lawrence A. Larson

Department of Pediatrics, Mayo Clinic and Mayo Foundation, Rochester, Minnesota

Edward J. O'Connell

Department of Pediatrics, Mayo Clinic and Mayo Foundation, Rochester, Minnesota

Duane M. Ilstrup

Section of Medical Research Statistics, Mayo Clinic and Mayo Foundation, Rochester, Minnesota

Studies within the last 20 years have shown that the incidence of asthma is increased in children who have been hospitalized with bronchiolitis due to respiratory syncytial virus. To evaluate such respiratory consequences in an ambulatory population, a follow-up study was done of 37 children who had respiratory syncytial virus infection documented at a community pediatric clinic in 1968 when they were younger than 4 years. This study, done ten years later by chart review and parental interview, showed that asthma had sub sequently been diagnosed in three (8%). Thus, an increased risk for the development of asthma after respiratory syncytial virus infection was not found. Comparison of these data with those from previous reviews questions a causative role for respiratory syncytial virus in childhood asthma.

Clinical Pediatrics, Vol. 20, No. 3, 187-190 (1981)
DOI: 10.1177/000992288102000303
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