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Clinical Pediatrics
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Neonatal Hypernatremic Dehydration Due to Excessively Concentrated Prepared Milk Formula

Emanuel Birenbaum

Neonatal Department, Chaim Sheba Medical Center, and Sackler School of Medicine, Tel-Aviv University, Tel-Hashomer, Israel

Eli Shahar

Neonatal Department, Chaim Sheba Medical Center, and Sackler School of Medicine, Tel-Aviv University, Tel-Hashomer, Israel

Mordechay Aladjem

Neonatal Department, Chaim Sheba Medical Center, and Sackler School of Medicine, Tel-Aviv University, Tel-Hashomer, Israel

Michael Brish

Neonatal Department, Chaim Sheba Medical Center, and Sackler School of Medicine, Tel-Aviv University, Tel-Hashomer, Israel

Excessively concentrated milk formula was administered accidentally to five newborn infants. Diarrhea, dehydration, hypernatremia, and hyperosmolality were present in all of them. Abnormal neurologic manifestations during the acute disease were observed in one infant. On follow-up, psychomotor devel opment and electroencephalographic recordings were normal in four infants. One infant, in whom accelerated growth of head circumference had been noted before the episode of diarrhea, was found to have obstruction of the foramen of Monro at the age of 6 weeks. Possible errors in preparing milk formulas by medical staff resulting in hypertonic dehydration are stressed in this report.

Clinical Pediatrics, Vol. 20, No. 10, 627-629 (1981)
DOI: 10.1177/000992288102001003
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R. Listernick and E. Sidransky
Hypernatremic Dehydration in Children with Severe Psychomotor Retardation
Clinical Pediatrics, August 1, 1985; 24(8): 440 - 442.
[Abstract] [PDF]