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Clinical Pediatrics
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Meningitis

Update of Recommendations for the Neonate

Allan Friedman

From the Divisions of Infectious Diseases and General Pediatrics, the Children's Hospital of Philadelphia, University of Pennsylvania Medical School, Philadelphia, Pennsylvania

Gary Fleisher

From the Divisions of Infectious Diseases and General Pediatrics, the Children's Hospital of Philadelphia, University of Pennsylvania Medical School, Philadelphia, Pennsylvania

Our series of children with meningitis shows an increase in the frequency of isolation of Hemophilus influenzae type B. This increase is most marked among children between one and two months of age. Since H. influenzae was found in five of the seven children between thirty and sixty days of age, we recommend the use of chloramphenicol for the initial treatment of bacterial meningitis after the first month of life. Additionally, our mortality data suggest that early diagnosis and intensive supportive therapy can contribute to a further decrease in the fatality rate of this disease.

Clinical Pediatrics, Vol. 19, No. 6, 395-397 (1980)
DOI: 10.1177/000992288001900603
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Home page
 Arch Pediatr Adolesc MedHome page
R. W. Enzenauer and J. W. Bass
Initial Antibiotic Treatment of Purulent Meningitis in Infants 1 to 2 Months of Age
Arch Pediatr Adolesc Med, November 1, 1983; 137(11): 1055 - 1056.
[Abstract] [PDF]