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Clinical Pediatrics
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*AMPICILLIN
*CEPHALEXIN
*SULFAMETHOXAZOLE
*TRIMETHOPRIM
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*Urinary Tract Infections
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Urinary Tract Infections in Children

Effect of Short Course Antibiotic Therapy on Recurrence Rate in Children with Previous Infections

R.S. Fennell

University of Florida College of Medicine, Department of Pediatrics, Division of Nephrology, Box J-296, JHMHC, Gainesville, FL 32610

M. Luengnaruemitchai

A. Iravani

E.H. Garin

R.D. Walker

G.A. Richard

Eighty-five girls, ages 3-16, with a past history of recurrent urinary tract infections were treated for 10 days with either trimethoprim/sulfamethoxazole, ampicillin or cephalexin. Patients with normal roentgenograms as well as those with reflux and cortical scarring were included. In the 12 weeks following completion of treatment, a significantly lower recurrence rate was noted in children who received trimethoprim/sulfamethoxazole. There was no differ ence in the recurrence rate whether or not radiographic abnormalities were present. No serious side effects were noted with any drug regimen.

Clinical Pediatrics, Vol. 19, No. 2, 121-124 (1980)
DOI: 10.1177/000992288001900206
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