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Clinical Pediatrics
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Shwachman-Diamond Syndrome and Chronic Liver Disease

William M. Liebman

Department of Pediatrics, Gastroenterology Unit University of California, School of Medicine, San Francisco, California

Eldad Rosental

Department of Pediatrics, Gastroenterology Unit University of California, School of Medicine, San Francisco, California

Moshe Hirschberger

Department of Pediatrics, Gastroenterology Unit University of California, School of Medicine, San Francisco, California

M. Michael Thaler

Department of Pediatrics, Gastroenterology Unit University of California, School of Medicine, San Francisco, California

Clinically inapparent persistent chronic liver disease in a 15-month-old male patient with Shwachman-Diamond syndrome is presented. Cryptic hepatic involvement may be an unrecognized feature of the syndrome and should be evaluated in all cases.

Clinical Pediatrics, Vol. 18, No. 11, 695-698 (1979)
DOI: 10.1177/000992287901801106
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Loss of the Mouse Ortholog of the Shwachman-Diamond Syndrome Gene (Sbds) Results in Early Embryonic Lethality
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