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Clinical Pediatrics
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Cholestyramine Treatment of Chronic Diarrhea Associated with Immune Deficiency Syndrome

Yoram Bujanover

Divisions of Gastroenterology and Immunology, Department of Pediatrics, University of California School of Medicine, San Francisco, California

Peter Sullivan

Divisions of Gastroenterology and Immunology, Department of Pediatrics, University of California School of Medicine, San Francisco, California

William M. Liebman

Divisions of Gastroenterology and Immunology, Department of Pediatrics, University of California School of Medicine, San Francisco, California

Joseph Goodman

Divisions of Gastroenterology and Immunology, Department of Pediatrics, University of California School of Medicine, San Francisco, California

M. Michael Thaler

Divisions of Gastroenterology and Immunology, Department of Pediatrics, University of California School of Medicine, San Francisco, California

A 5-year-old boy with known severe combined immunodeficiency disease presented with chronic diarrhea, malabsorption and retarded growth. Candida albicans was found in distal duodenal fluid, and invading the intestinal mucosa. Chronic diarrhea persisted after antimycotic therapy, but responded to treat ment with cholestyramine. Repeated courses of cholestyramine resin over a 6-month period were required for complete resolution of the gastrointestinal symptomatology.

Clinical Pediatrics, Vol. 18, No. 10, 630-633 (1979)
DOI: 10.1177/000992287901801012
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