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Clinical Pediatrics
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Systemic Lupus Erythematosus in Children

The Complex Problems of Diagnosis and Treatment Encountered in 101 Such Patients at the Mayo Clinic

Donald G. Norris, M.D.

Angel R. Colón, M.D.

Gunnar B. Stickler, M.D.

Junior Faculty Clinical Fellow of the American Cancer Society in Pediatric Oncology

Between 1945 and 1970, 101 children (86 girls and 15 boys) with systemic lupus erythematosus were evaluated at the Mayo Clinic. Only 9 children were less than 9 years old at the time of diagnosis. The most frequent presenting complaint was arthralgia; fever, fatigue, and a "butterfly" malar rash also were common. Renal involvement, found in more than 76 per cent of patients, was a prognostically poor sign. The overall survival of children with renal involvement is improved by the use of adequate steroid therapy.

Clinical Pediatrics, Vol. 16, No. 9, 774-778 (1977)
DOI: 10.1177/000992287701600906
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