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Clinical Pediatrics, Vol. 16, No. 7, 639-644 (1977)
DOI: 10.1177/000992287701600710
© 1977 SAGE Publications

Cephalexin: Clinical and Laboratory Evaluation in Infants and Children

R.C. Rudoy, M.D.

Department of Pediatrics and the Pediatric Pharmacology Unit, Children's Memorial Hospital, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73190

Harris D. Riley, JR., M.D.

Department of Pediatrics and the Pediatric Pharmacology Unit, Children's Memorial Hospital, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73190

Cephalexin appears to be a highly effective antibiotic. It possesses the qualities of rapid oral absorption, production of high drug levels in the blood and urine, and near absence of side effects. it is effective against infections due to gram-positive cocci infections, with the exception of Enterococcus, and for most infections caused by E. coli and Klebsiella. It is useful in the treatment of a wide variety of infections in infants and children, and particularly valuable with susceptible infections in patients who do not require parenteral antimicrobial therapy.


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