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Clinical Pediatrics
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The Clinical Profile of the Newborn with Persistent Pulmonary Hypertension

Observations in 19 Affected Neonates

Willa H. Drummond

Divisions of Neonatology and Cardiology, The Children's Hospital of Philadelphia and The University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania

George J. Peckham

Divisions of Neonatology and Cardiology, The Children's Hospital of Philadelphia and The University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania

William W. Fox

Divisions of Neonatology and Cardiology, The Children's Hospital of Philadelphia and The University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania

In 19 neonates with severe cyanosis, normal chest x-rays, anatomically normal hearts, and a high incidence of perinatal complications, the clinical course was characterized by variable sustained cyanosis. Cardiac catheteriza tion data showed high systemic or suprasystemic pulmonary artery pressure with right to left intracardiac shunting via the foramen ovale and ductus arteriosus. Arterial oxygen tension at an inspired oxygen concentration above 65 per cent was helpful in distinguishing these patients from those with congenital heart disease, and for predicting prognosis.

Clinical Pediatrics, Vol. 16, No. 4, 335-341 (1977)
DOI: 10.1177/000992287701600407
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This article has been cited by other articles:


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J. F. Watchko
Persistent Pulmonary Hypertension in a Very Low Birthweight Preterm Infant
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 Arch Pediatr Adolesc MedHome page
J. R. Hageman, M. A. Adams, and T. H. Gardner
Persistent Pulmonary Hypertension of the Newborn: Trends in Incidence, Diagnosis, and Management
Arch Pediatr Adolesc Med, June 1, 1984; 138(6): 592 - 595.
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 CLIN PEDIATRHome page
S. H. Fakhraee, O. P. Mathew, E. Yang, F. R. Gutierrez, and R. E. Marshall
Obstructed Total Anomalous Pulmonary Venous Return Confused with Persistent Pulmonary Hypertension of the Newborn
Clinical Pediatrics, September 1, 1980; 19(9): 644 - 645.
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