Clinical Pediatrics

 

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Clinical Pediatrics, Vol. 15, No. 7, 645-650 (1976)
DOI: 10.1177/000992287601500716


Reviews

Clinical Review : Renal Tubular Acidosis: Practical Guides to Diagnosis and Treatment

Gladys H. Hirschman

Department of Nephrology, Children's Hospital National Medical Center, Department of Child Health and Development, George Washington University Medical Center, and the Department of Pediatrics, Howard University School of Medicine, Washington, D.C.

David D. Rao

Department of Nephrology, Children's Hospital National Medical Center, Department of Child Health and Development, George Washington University Medical Center, and the Department of Pediatrics, Howard University School of Medicine, Washington, D.C.

Olusola Oyemade

James C. M. Chan

Department of Nephrology, Children's Hospital National Medical Center, Department of Child Health and Development, George Washington University Medical Center, and the Department of Pediatrics, Howard University School of Medicine, Washington, D.C.

The syndrome of renal tubular acidosis in some one of its various forms should be suspected when an infant or child has failure to thrive, metabolic acidosis, constipation, diarrhea, vomiting, anorexia, polyuria, or dehydra tion in infancy. Confirmatory biochemical findings include an inappropriately high urinary pH, inadequate acid excretion and/or abnormal tubular reab sorption of filtered bicarbonate.

Growth can be normal when there is sustained correction of the metabolic acidosis through appropriate alkaline therapy.


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