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Prolonged Apnea of Prematurity

Treatment with Continuous Airway Distending Pressure Delivered by Nasopharyngeal Tube

Children's Hospital, St. Paul, Minn., Department of Pediatrics, University of Minnesota, Minneapolis, Minn.

John W. Reynolds

Recipient of National Institutes of Health Career Development Award 5-KO3-HD-09688

Five premature infants experiencing frequent episodes of apnea and bradycardia were treated with continuous positive airway pressure deliv ered by nasopharyngeal tube. A significant de crease in the frequency and severity of apneic spells was observed. Premature withdrawal from end expiratory pressure resulted in an increase in both the incidence and the duration of the apneic episodes. We suggest that hypoventilation and a reduced functional residual capacity (FRC) are related to the development of prolonged apnea. Expansion and stabilization of FRC with small amounts of end expiratory pressure appears to be beneficial.

Clinical Pediatrics, Vol. 15, No. 2, 123-134 (1976)
DOI: 10.1177/000992287601500203


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