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Neonatal Sepsis

A Survey of Eight Years' Experience at the Louisville General Hospital

University of Louisville School of Medicine, Louisville, Ky. 40202

Billy F. Andrews, M.D.

Department of Pediatrics, University of Louisville School of Medicine, Louisville, Ky. 40202

Information from 50 infants with neonatal septicemia from the Louisville General Hospital during an eight-year period (1964-1972) is presented. Twenty-five infants had gram-positive and the other 25 had gram-negative organisms. E. coli (13 cases), Staphylococcus (10 cases), and hemolytic Streptococcus non-Group A (7 cases) were the most common causative microorganisms. Only one of the 25 infants with gram-positive sepsis died; three with gram-negative sepsis died. Listeria monocytogenes was demonstrated in three infants; all had meningitis with no mortality. Early diagnosis, prompt intensive antibacterial therapy, and a high index of suspicion are most helpful for reducing the morbidity and mortal ity.

Clinical Pediatrics, Vol. 14, No. 2, 181-185 (1975)
DOI: 10.1177/000992287501400209


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