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Clinical Pediatrics, Vol. 12, No. 6, 310-314 (1973)
DOI: 10.1177/000992287301200619

Central Nervous System Infections in Hydrocephalus or Myelodysplasia

Factors Which Influence Mortality and Recovery

David B. Shurtleff, M.D.

Professor and Head, Division of Congenital Defects, Department of Pediatrics, University of Washington School of Medicine, Seattle, Wash

Review of the literature and experience with 19 CNS infections in infants with CNS malformations suggest prognosis is not worse with neonates with mal formations and is directly related to virulence of the infecting organism. Re covery is also dependent on treatment that will provide bacteriocidal levels of antibiotic into the infected tissue and fluids and on correction of disturbed in tracranial fluid dynamics, both tissue fluid (edema) and cerebrospinal fluid.


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