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Clinical Pediatrics
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Clinical Evaluation of an Epinephrine Suspension in the Treatment of Asthma

Jose Lozano

Allergy Division, Department of Medicine, Children's Hospital Medical Center, Department of Pediatrics, Harvard Medical School, Boston

Walter McLean

Allergy Division, Department of Medicine, Children's Hospital Medical Center, Department of Pediatrics, Harvard Medical School, Boston

Paul Hannaway

Allergy Division, Department of Medicine, Children's Hospital Medical Center, Department of Pediatrics, Harvard Medical School, Boston

Harry Mueller

Allergy Division, Department of Medicine, Children's Hospital Medical Center, Department of Pediatrics, Harvard Medical School, Boston

This study was carried out with 50 asthmatic children to evaluate the speed of action of Sus-Phrine,{ddagger} which is epinephrine in a concentration of 1: 200, of which approximately 20 per cent is in solution for an immediate effect with the remainder in suspension for sustained action. The data indicated that Sus-Phrine is comparable to aqueous epinephrine in the rapidity of its bron chodilating effect. Because of its well-established prolonged action, this may be the drug of choice for the initial injection of epinephrine in acute asthma.

Clinical Pediatrics, Vol. 11, No. 9, 499-502 (1972)
DOI: 10.1177/000992287201100904
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