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Diagnosis of Down's Syndrome: Clinical vs. Laboratory

Departments of Preventive Medicine and Pediatrics, University of Mississippi Medical Center, 2500 North State Street, Jackson, Mississippi 39216

John F. Jackson

Departments of Preventive Medicine and Pediatrics, University of Mississippi Medical Center, 2500 North State Street, Jackson, Mississippi 39216

The art of simple physical examination is still valuable. Faced with a child suspected of having Down's syndrome, a lack of facilities for chromosome analysis, and anxious parents, the physician can often make the diagnosis with a high degree of accuracy by a thor ough physical examination, performed with the help of a check-list of frequently found signs. This paper compares the results of physi cal examination with those of chromosome analysis in 150 patients.

Clinical Pediatrics, Vol. 11, No. 6, 353-356 (1972)
DOI: 10.1177/000992287201100610


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