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Clinical Pediatrics
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Ampicillin Failure in H. Influenzae Meningitis

A Case Report with Added Commentaries

Stephen R. Kandall, M.D.

U. S. Public Health Service Hospital, New Orleans, La.

Thomas C. Davis, M.D.

U. S. Public Health Service Hospital, New Orleans, La.

Mark Abramowicz, M.D.

Department of Pediatrics, Albert Einstein College of Medicine, Bronx, N. Y.

The authors describe a child whose H. influenzae menin gitis persisted despite relatively high-dose ampicillin ther apy. They raise the question whether longterm morbidity from H. influenzae meningitis may be greater with ampicil lin than with the older chloramphenicol-penicillin treatment. Two experts were asked to discuss this question in the light of this case report. Their comments follow the main paper.

Clinical Pediatrics, Vol. 11, No. 5, 264-267 (1972)
DOI: 10.1177/000992287201100507
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 Arch Pediatr Adolesc MedHome page
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Arch Pediatr Adolesc Med, January 1, 1977; 131(1): 46 - 48.
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 Arch Pediatr Adolesc MedHome page
H. D. Wilson and K. C. Haltalin
Ampicillin in Haemophilus influenzae Meningitis: Clinicopharmacologic Evaluation of Intramuscular vs Intravenous Administration
Arch Pediatr Adolesc Med, February 1, 1975; 129(2): 208 - 215.
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