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Clinical Pediatrics
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Hematologic and Biochemical Studies of Turkish Children With Pica

A Presumptive Explanation for the Syndrome of Geophagia, Iron Deficiency Anemia, Hepatosplenomegaly and Hypogonadism

Ayhan OkçuoGlu Çavdar, M.D.

Ayten Arcasoy, M.D.

Professor and Associate Professor of Pediatrics (Hematology), School of Medicine, Ankara University, Ankara, Turkey

The present study clearly indicates the presence of iron deficiency anemia in Turkish children with long standing pica for soil and clay. Most of the patients described had marked growth retardation and a lag in bone age. As explanation, the cations in soil and clay seem to enter into an ion exchange retention reaction with dietary iron, zinc and perhaps other trace metals, resulting in the typical complex of deficiency symptoms.

Clinical Pediatrics, Vol. 11, No. 4, 215-227 (1972)
DOI: 10.1177/000992287201100408
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