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Efficacy of Fixed Combination Antibiotics versus Separate Components in Otitis MediaEffectiveness of Erythromycin Estolate, Triple Sulfonamide, Ampicillin, Erythromycin Estolate-Triple Sulfonamide, and Placebo in 280 Patients with Acute Otitis Media Under Two and One-Hal Years of Age
Virgil M. Howie, M.D., F.A.A.P.
John H. Ploussard, M.D.
2345 Whiteshurg Drive South, Huntsville, Alabama 35801. Associated with Huntsville (Alabama) Hospital
Ampicillin and a fixed combination of erythromycin estolate-triple sulfonamide suspension proved equally effective in eradicating or ganisms and exudate in otitis media. Triple sulfonamide was not as effective as a number of other drugs tested for eliminating the pneu mococcus, and erythromycin estolate was not as effective as the fixed combination or ampicillin with Hemophilus influenzae.
Clinical Pediatrics, Vol. 11, No. 4,
205-214 (1972)
DOI: 10.1177/000992287201100407

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