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Clinical Pediatrics
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Problems in the Diagnosis and Management of Acute Leukemia in Childhood

Comments Based on a Survey of 100 Recent Patients

Audrey E. Evans

The Children's Hospital of Philadelphia, 1740 Bainbridge Street, Philadelphia, Pennsylvania 19146

Irving J. Wolman

The Children's Hospital of Philadelphia, 1740 Bainbridge Street, Philadelphia, Pennsylvania 19146

The early recognition of leukemia rests on a heightened awareness of the possibility of this disease in children with obscure symptoms. Once suspected, confirmation of the diagnosis is not difficult. The natural history of the disease has altered considerably in the past ten years due, in large part, to the increased survival. Problems of infection and localized collections of leukemic cells are now of major importance when trying to support patients in relapse.

Clinical Pediatrics, Vol. 10, No. 10, 571-575 (1971)
DOI: 10.1177/000992287101001010
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