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Clinical Pediatrics, Vol. 10, No. 10, 561-565 (1971)
DOI: 10.1177/000992287101001006

Renal Anomalies in Turner's Syndrome

Types and Suggested Embryogenesis

Fred Matthies

Departments of Medicine and Pediatrics and the Laboratory for the Study of Hereditary and Metabolic Disorders, University of Utah College of Medicine, Salt Lake City, Utah

W.D. Macdiarmid

University of Utah College of Medicine, Salt Lake City, Utah

Marvin L. Rallison

University of Utah College of Medicine, Salt Lake City, Utah

Frank H. Tyler

University of Utah College of Medicine, Salt Lake City, Utah

Of 15 patients with Turner's syndrome studied for renal anomalies by intravenous pyelogram, 11 had demonstrable abnormalities ; three had horseshoe kidney. None had evidence of impaired renal func tion. Four reported previous urinary tract infections. Similarities among the positional and structural abnormalities of the kidneys suggested a continuum of morphologic changes, with a possible re lationship of such changes to impaired positional information pro gramming by the developing abnormal gonad during embryogenesis.


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