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Clinical Pediatrics
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Article

Preterm Premature Rupture of Membranes: Clinical Outcomes of Late-Preterm Infants

Julio Mateus, MD*, Karin Fox, Sangeeta Jain, Sunil Jain, Richard Latta, and Jerry Cohen

* To whom correspondence should be addressed. E-mail: jfmateus{at}utmb.edu.


  Abstract
Objective: To determine gestational age-specific neonatal outcomes of late preterm infants delivered as a consequence of premature rupture of membranes (PROM). Methods: Retrospective cohort study of infants born to women delivered electively due to preterm PROM between 340/7 and 366/7 weeks of gestation. Neonatal outcomes were compared between those delivered at 340/7 to 346/7 weeks, at 350/7 to 356/7 weeks, and at 360/7 to 366/7 weeks. Results: 192 infants were identified.The 340/7 to 346/7 week infants had significantly higher neonatal intensive care admission rate (72.5%) compared to those at 350/7 to 356/7 weeks (22.8%) and at 36 to 366/7 weeks (17.8%) (P < .05). Neonatal respiratory distress syndrome was significantly higher at 340/7 to 346/7 weeks (35.4%) compared with 350/7 to 356/7 week and 360/7 to 366/7 week infants (10.5% and 4.1%; P < .05).The longest hospitalization occurred in the 340/7 to 346/7 week infants (248.5 ± 20.0 hours). Conclusion: Substantial short-term morbidity occurred in late preterm infants.The greatest number of complications affected infants born at 340/7 to 346/7 weeks.

First published on July 30, 2009
Clinical Pediatrics 2009, doi:10.1177/0009922809342460
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